A clinical evaluation was made on patients with urinary tract infection following urinary instrumentation for diagnosis and treatment. 60 patients included in this study necessitated a short or long term urinary catheterization with Foley´s catheters. These patients were hospitalized at St. Mary´s Hospital, Catholic Medical College, during the period of January through August, 1970 for this study.
Regular urine samples for culture were obtained every other day.
The results were as follows:
1. Growth of micro-organisms on culture showed statistically a slight increase in female as compared with male (27:21). 40 of 60 patients(66.7%) turned out to be positive on culture. 26 of 60 patients were females in whom 19 patients were positive on culture (73.1%). 34 of 69 patients were males in whom 21 patients were positive on culture(61.8%). Mixed infections were observed only in females. 16 of 25 patients (64%) with "negative" on first culture became positive on the second.
2. 8 cases of mixed infections were observed such as klebsiella and E. coli, or E. coli and enterococcus, ect (13.3%).
3. Most of micro-organisms recovered by culture were gram negative (92.8%). Klebsiella predominated (50%) and E. coli relatively common (27.1%).
4. On sensitivity tests to the various antibiotics,. 25% of E. coli was sensitive to kanamycin and 10.7% to tetracycline and chloramphenicol. Klebsiella was also sensitive to kanamycin (15.2%) and chloramphenicol(10.5%), while some klebsiella strains were resistant to all tested antibiotics(23.7%).
In general, most of the other micro-organisms showed sensitivity to either kanamycin and chlorampenicol.
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